Fatty liver disease spirals in India since 1990, driven by diabetes and obesity: Study raises red flags

Fatty liver disease spirals in India since 1990, driven by diabetes and obesity: Study raises red flags

4 min readNovel DelhiUp to this level: Apr 14, 2026 11:25 AM IST

fatty liverDr Palnitkar talked about it was no longer uncommon for practically every sanatorium to have a fatty liver sanatorium. (Representational image/File)

About one in six of us worldwide — 16% of the worldwide inhabitants — were living with metabolic dysfunction-associated steatotic liver illness (MASLD) or what we know as non-alcoholic fatty liver illness in 2023, marking a 143% amplify since 1990.

India has proven a engaging upward thrust in MASLD incidence, up 23.19 per cent from 1990 to 2023. India’s age-standardised MASLD incidence payment rose from 10,191 per 100,000 in 1990 to 12,555 per 100,000 in 2023. The findings, revealed in The Lancet Gastroenterology and Hepatology, repeat that the spike is extra and extra pushed by rising metabolic risk factors, in conjunction with excessive blood sugar and weight problems.

“India’s case spiral aligns with South Asian patterns, pushed by metabolic dangers amid inhabitants growth,” Dr Mahaveer Golechha, Professor, IIPH-Gandhinagar and contributing author of the World Burden of Illnesses, 2023, educated The Indian Suppose. He also explained that there had been a microscopic drop in DALYs (Incapacity-Adjusted Life Years, a metric representing years of healthy lifestyles lost in consequence of illness, incapacity, or untimely loss of life). As per the look, the age-standardised DALY payment for MASLD in India fell a piece of from 23.8 per 100,000 in 1990 to 21.1 per 100,000 in 2023, a 11.3 per cent decrease.

What are the most significant risk factors for fatty liver?

“High fasting plasma glucose, adopted by excessive BMI (physique mass index) and smoking in India reflect global patterns where blood glucose phases power 2.2 DALYs per 100,000. Decrease healthcare derive admission to correlates with bigger DALYs in countries enjoy India,” Dr Goleccha explains.

“It is some distance serious to elevate awareness about liver health, the 2d largest organ within the human physique. The 2026 theme is ‘Trusty Habits, Trusty Liver,’ and focusses on fixed each day life decisions — goal like a nutritious weight-reduction diagram, exercise and limiting alcohol — which may maybe presumably well be vital for combating liver ailments, 90% of which may maybe presumably well be preventable,” talked about Dr Sachin Palnitkar, consulting hepatologist at Deenanath Mangeshkar Correctly being facility, Pune.

Takeaways from look

The look affords an outline of the worldwide, regional, and nationwide burden of MASLD across 204 countries. MASLD incidence rose practically 29% from 1990 to 2023, while the DALY payment remained genuine—suggesting improved care may maybe presumably well be delaying severe illness, nonetheless also leaving a rising inhabitants liable to complications enjoy cirrhosis and liver most cancers. MASLD is projected to have an affect on 1.8 billion of us by 2050, a 42% amplify from 2023, with enhance pushed largely by inhabitants growth in favor to increasing outdated on my own.

MSALD rising in India nonetheless info silent scarce

In an earlier look within the Lancet Regional Correctly being South Asia this yr, authors Meghana Arvind and others had flagged that community-essentially based completely completely info dwell scarce. They had talked about, while there are dinky analysis accessible for community-huge incidence of MASLD within the total inhabitants in India, the incidence of NAFLD is alarmingly excessive, ranging from 9 to 32% in urban areas, with clear areas reporting a incidence of practically 60%, attributed to fast urbanisation, sedentary lifestyles and dietary shifts toward processed, calorie-dense foods.

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Dr Palnitkar talked about it was no longer uncommon for practically every sanatorium to have a fatty liver sanatorium. “The foremost trigger is insulin resistance. The assortment of instances has elevated severely over time. Earlier, only about 5–10% of patients were diagnosed with fatty liver, nonetheless now practically 15–20 out of every 60 patients have this condition at my on a typical foundation OPD,” he talked about.

Increasing assortment of youthful adults with MASLD

What’s extra concerning is that youthful of us are extra and extra being affected. “There is an pressing need for structured awareness programmes, particularly since fatty liver is a reversible condition if detected early,” Dr Palnitkar talked about. As per the look too, an vital assortment of of us living with MASLD was in youthful adults (round ages 35-39 for men and 55-59 for females).

High blood sugar the leading trigger

High blood sugar was the leading driver of MASLD-connected health loss globally, adopted by excessive BMI and smoking, highlighting solid hyperlinks to diabetes and weight problems. What was a field may maybe presumably well even be the asymptomatic nature of early-stage MASLD generally results in delayed diagnosis. So, strengthening prevention, increasing screening and making improvements to treatment will likely be serious —particularly in settings with lower health-care derive admission to and quality.

Anuradha Mascarenhas

Anuradha Mascarenhas is a Senior Editor at The Indian Suppose, essentially based completely completely in Pune. With a career spanning three decades, she is surely one of many most beneficial voices in Indian journalism concerning healthcare, science and atmosphere and analysis inclinations. She also takes a eager hobby in protecting females’s disorders .

Professional Background

Education: A gold medalist in Communication and Journalism from Savitribai Phule Pune University and a Master’s degree in Literature.

Author: She authored the biography At The Wheel Of Analysis, which chronicles the lifestyles and work of Dr. Soumya Swaminathan, the oldschool Chief Scientist on the WHO.

Key Focal level: She combines scientific accuracy with storytelling, translating complicated clinical analysis into compelling public and human-hobby narratives.

Awards and Recognition

Anuradha has acquired loads of awards in conjunction with the Press Council of India’s nationwide award for excellence in journalism below the gender essentially based completely completely reporting class in 2019 and the Laadli Media award (gender sensitivity -2024). A recipient of the Lokmat journalism award (gender class-2022), she was also shortlisted for the RedInk awards for excellence in journalism-2021. Her debut book At The Wheel Of Analysis, an uncommon biography of Dr Soumya Swaminathan the inaugural chief scientist of World Correctly being Organisation was also nominated within the Well-liked Replace Category of JK Paper AUTHER awards. She has also secured competitive fellowships in conjunction with the Laadli Media Fellowship (2022), the Survivors In opposition to TB – Novel Analysis in TB Media Fellowship (2023) and is a a part of the popular 2025 India Cohort of the WomenLift Correctly being Management Dart.”

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Signature Beat: Correctly being, Science & Women in Management

Anuradha is important for her COVID-19 reportage, where she was surely one of many first journalists to present detailed insights into the Covishield and Covaxin trials. She has a dedicated hobby in gender differ in health and science, generally profiling females researchers who’re breaking the “leaky pipeline” in STEM fields. Her writing vogue is scrupulous, generally that comprises interviews with high-tier scientists and health experts from a wonderful deal of institutions.

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